Histopathology & Cytopathology

Histopathology and Cytopathology, both have been powerful services provided by Trulife Diagnostics. Under this department, we provide full specialized testing under all-important therapeutic sectors. Our team of histopathology discussed closely with technicians to comprehend case histories, coordinate the results clinically, and help in the decision-making process.

Also, we provide a perfect bouquet of IHC markers for a complete diagnosis.

ONCOPATHOLOGY (MESENCHYMAL, EPITHELIAL & HEMATOLYMPHOID NEOPLASMS)
Wide range reporting and grossing as per the standard CAR protocols and updated tumour classifications.

All are related to diagnostic as well as predictive IHC markers

GI PATHOLOGY (ENDOSCOPIC BIOPSY & LIVER BIOPSY)
Complete and perfect reporting of GI endoscopic biopsies along with right special stains and IHC, where needed.

Liver biopsies reporting with all necessary special stains like PAS, Rhodamine, PAS-AD, Masson’s Trichrome, Reticulin, Prussian Blue)

NEPHROPATHOLOGY & UROPATHOLOGY
Comprehensive and correct reporting of renal biopsies with all particular stains like PAS, Masson’s Trichrome, Silver and Congo Red and Direct Immunofluorescence like IgG, IgM, IgA, C3, C1q, C4d, and kappa and lambda light chains.

Coverage of prostatic tissue like Needle biopsies and TURP specimens, resection specimens (nephrectomy, cystectomy, and prostatectomy), and bladder biopsies (TURBT).

OROPHARYNGEAL, LARYNGEAL & BRONCHIAL/PULMONARY PATHOLOGY
Salivary gland biopsies/excisions, Oral mucosal biopsies, non-neoplastic lesions, maxillary/mandibular tumours, laryngeal biopsies, transbronchial lung biopsies, bronchial biopsies, and core biopsies from lung as well as mediastinal lesions

GYNAEC PATHOLOGY
Cervical biopsies and Endometrial, and resection specimens

OTHERS
Biopsies from any part of the body like ocular, ear, skin, CNS, peritoneal, etc)

IHC (Immunohistochemistry)
Immunohistochemistry (IHC) is the procedure of immunological, anatomical, and biochemical techniques to distinguish discrete tissue components by the target antigens dealings with a few antibodies tagged with a visible label.

IHC helps to visualize the localization and distribution and specific cellular components within the cells as well as in the accurate tissue context.

Effectiveness of IHC:

Diagnostic applications
Badly differentiated malignant tumour
Malignant small round cell tumour
Typing / Sub categorization of lymphomas
classification of key sites in metastatic adenocarcinoma
Typing of mesenchymal tumours
As predictive markers in malignancy
To forecast the prediction of tumours by recognizing tumour-specific antigens, enzymes, oncogenes, tumour cell proliferation markers, and tumour suppressor genes
Forecast of response to therapy
Analytical markers for breast carcinoma (PR, ER, and HER2), B-cell non-Hodgkin's lymphoma (CD 20), and gastrointestinal stoma tumours (CD117), etc
Infections
Immunohistochemical methods are used to validate infectious agents present in tissues by utilization of different antibodies against microbial DNA or RNA such as in Hepatitis B virus, Cytomegalovirus, Hepatitis C virus, BK Polyomavirus (SV40), H. Pylori, etc.